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LITHOPROBE is supported on a continuing basis by a collaborative special project research grant from the Natural Sciences and Engineering Research Council of Canada (NSERC) and through the regular budget of the Geological Survey of Canada (GSC). NSERC is a quasi-independent agency within Industry Canada which has as its mission fostering the discovery and application of knowledge through the support of university research and the training of scientists and engineers. NSERC supports both basic university research through research grants and project research through partnerships of universities with governments and industry. NSERC does this by awarding grants and scholarships through a peer-reviewed competitive process and by building the partnerships.

The Geological Survey of Canada is a 155 year-old scientific institution of the federal government which is part of the Earth Sciences Sector of Natural Resources Canada. Its principal activity is the generation and dissemination of geoscience information to meet a variety of purposes. The GSC's present mission is "to provide Canada with a comprehensive geoscience knowledge base contributing to economic growth, sustainable development, health and safety, and environmental protection by acquiring, interpreting and disseminating geoscience information concerning Canada's landmass and offshore territory".

When the scientific program of LITHOPROBE takes place in a particular province or territory, scientists from the provincial or territorial geological surveys often take part. Support for their activities is derived from their government budgets, representing an important contribution to the overall collaborative program of LITHOPROBE. Similarly, when the scientific activities are in a region of interest to industry or involve techniques of interest to industry, LITHOPROBE activities often derive both direct financial support and provision of scientific data or information from the private sector. One example of industry support is the contribution of part of the funds required for a large, crustal penetrating (i.e., to about 50 km depth) seismic reflection survey in northwestern Alberta.

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